10 Glycolysis Facts

1. Glycolysis aka the Embden-Meyerhof-Parnas pathway (EMP pathway) was discovered by Gustav Embden, Otto Meyerhof and Jakub Karol Parnas.

2. The Glycolysis process is so old that it has probably been around before oxygen made its debut in the atmosphere.

3. Glyco –glucose Lysis- splits. It basically is the conversion of one 6-carbon glucose molecule into two 3-carbon sugars called pyruvate through a series of enzymatic reactions.

4. It involves two phases, the Preparatory phase or the energy investment phase and the energy generation phase or the payoff phase.

5. In the investment phase, initially 2 ATP molecules are invested in glycolysis.  The payoff is the generation of 4 ATP molecules so a profit or net gain of 2 ATP molecules is made.

6. Glycolysis involves 10 reactions each being catalyzed by one of ten enzymes, in the following order Hexokinase, Phosphohexose Isomerase, Phospho- fructokinase -1, Aldose, Triose phosphate isomerase, Glyceraldehyde 3- phosphate, Phosphoglycerate kinase, Phosphoglycerate mutase, Enolase and finally Pyruvate kinase.

7. It occurs in plant and animal cells and the cells of microbes.

8. It occurs in the cytoplasm of prokaryotes and the cytosol of eukaryotes.

9. Under anaerobic conditions, glycolysis causes cells to produce ATP. This process is called fermentation.

10. Under aerobic conditions, glycolysis is the first phase of cellular respiration.



Posted on March 17, 2014, in Uncategorized. Bookmark the permalink. 2 Comments.

  1. uhm..so with regards to fact #2, I have a few queries…I see you used the word “probably” so does that mean that statement is opinion rather than fact? If no, then how did organisms facilitate the lack of the other metabolic pathways (krebs, followed by the ETC which needs O2) and oxygen..in terms of energy production because glycolysis only yields 2 ATP molecules (net gain) if I’m not mistaken….haha sorry this may seem like a long question, it’s not, maybe if you provided an example organism or something that would help 🙂

  2. I am sooo past questioning it..this post has gotten me interested hence that slightly long question there x_x

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