Monthly Archives: February 2014

Diary of wimpy Jimmy

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-Arie and Nandi

What we learnt from the story:

Proteins help to increase muscle mass hence the term ‘gains’. So what exactly are gains? o.O

There are many protein powders and shakes that help speed up this process. Some contain whey and casesin while most has glutamine. Glutamine is a non essential amino acid which simply means that the body produces it. Its function is to transport ammonia throughout the body so it flows in the bloodstream. During strenuous exercise, the need for glutamine in the blood increases as glutamine stores deplete therefore bodybuilders drink  proteins separately to increase the amount of glutamine  in their system.

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Secondarystructurelove.com

It seems that we have found out our friend’s, the alpha helix, secret online dating profile. Let’s see how he describes himself.

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-Ren and Nandi

HORROR STORY TIME

Let’s gather ’round kids cause its story time once again. The story of… Proline (dun DUN DUUUUUNN!!!!!!!!)

There was once this amino acid named Proline. It looks like a common a.a , it’s cyclic and non-polar and has a fused ring structure (seems pretty normal right?) WRONG!! This amino acid is far from normal. The alpha carbon and the alpha amino group bond to form this ring structure, but this leaves no hydrogen free to be donated and to stabilize the structure of the alpha helix or a beta pleated sheet, thereby disrupting the structure!

The victims of proline’s wrath are said to be left horribly disfigured (a slight bend/kink in the structure due to the lack of the H-bond present.)

Legend has it that proline is still seen around bends, and lurking at the end of the structures, plotting it’s revenge….BOO!!

Scared

-Ren

A Scary Story Of…

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The wind howled menacingly as the rain fell over AminoVille. It was 11pm and at the Peptide’s house, Proteins and their girlfriends, Hydrogens, were chilling on the couch watching Pro-teen Wolf. They watched the television intensely while they cuddled with their girlfriends. This made Proteins felt stable since they were really afraid of the show.

 Bam! A noise was heard coming from the outside. They all jumped and some Proteins messed their pants with amino acids. They laughed at each other but decided to take a look to see what had caused the noise. Their girlfriends were with them of course since the Proteins were wimps. To their relief it was just an amino acid residue branch that fell from the polypeptide tree. They continued watching their show.

 Bam! Again, the noise was heard but it was louder and closer this time. They all went outside on the porch gazing on, looking for what had made the sound. Then, all of a sudden, these thugs appeared from the dark of the night, Heat, Urea, Ethanol, Acetone and Acid and Base who looked very strong, surrounded them.

 They stuffed them in the trunk of the car and carried them to a creepy forested area and told each of them to line up. Proteins were scared out of their wits. The thugs then shouted, “We are going to denature you all!” The Proteins looked at each other; fear filled their eyes as they hugged their Hydrogen girlfriends tighter.

 The thugs then forced them to break up with their Hydrogen girlfriends. The proteins refused to but the thugs were too strong for them. After the break up, all the thugs began to laugh at how the Proteins looked. They looked like losers and wimpy without their Hydrogen girlfriends.

AND this my friends is how Proteins get denatured…well at least in my head :/ teehee.

-Nandi 2014

Quiz time….no pressure!

In an α-helix, how many amino acids are there per turn of the helix?

  1. 3.9
  2. 2.6
  3. 3.6
  4. 3.0
  5. 3.4

 

 

Amino acids Puzzle!

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-Andy

 

 

YouTube. “Amino acids and proteins pt 2.mov.” 2014. http://www.youtube.com/watch?v=ZWLNkEJloJA&feature=youtu.be (accessed 23 Feb 2014).

Rpi.edu. “Review: Protein Structure.” 2014. https://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/protein.htm (accessed 23 Feb 2014).

 Elmhurst.edu. “Secondary Protein.” 2014. http://www.elmhurst.edu/~chm/vchembook/566secprotein.html (accessed 23 Feb 2014).

 Biology.arizona.edu. “Amino Acids – Proline.” 2014. http://www.biology.arizona.edu/biochemistry/problem_sets/aa/proline.html (accessed 23 Feb 2014).

Russelllab.org. “Proline.” 2014. http://www.russelllab.org/aas/Pro.html (accessed 23 Feb 2014).

 

 

A Cloud of Words…..of the essential amino acids :D

A Cloud of Words.....of the essential amino acids :D

CHOOSE YOUR CHARACTER

All amino acids have the same groups attached to their alpha carbons (Hydrogen, an amino group and a carboxyl group) except the R-groups which gives the amino acid their different characteristics. So have fun choosing your favourite.

Glycine (Gly):

  • Non-polar
  • I have an aliphatic R- group (do not contain aromatic rings)
  • My R-group is just a hydrogen…. nothing fancy
  • I am the smallest amino acid possible and I’m really shy…

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Cysteine (Cys):

  • Polar
  • My R-group is neutral but I don’t really care…
  • If you get me together with another cysteine, things can get pretty wild. By losing both our hydrogens on our Sulphur Hydryl groups and forming a disulphide bond we can totally form into a Cystine bruh! We do crazy things when we’re oxidised!
  • But everyone knows the cure for an oxidation is a good reduction (am I right?) soo, if we get back 2 hydrogens then we go back to being Cysteine again (yawn!)

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Phenylalanine (Phe) *ugh mouth full*

  • I fall under the aromatic R-groups (because I’m so sweet)
  • My R-group is basically a hexagonal ring with double bonds arranged in a conjugated form
  • Some people even say that I have a beautiful benzene ring present *wink wink*

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Aspartate (Asp):

  • What are you lookin’ at? Yeah, I have a negatively charged R-group! What about it?
  • My R-group has a COOˉ present so you better not mess with me!

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Histidine (His):

  • Hi! I’m Histidine and I have a positively charged R-group because I look on the brighter side of life (hehehe)
  • Just kidding! My R-group is positive because I have a nitrogen which has four other bonds
  • Some people call me an essential amino acid because I can’t be synthesized by the human body but that’s ok because I can be obtained from your diet.

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Choose your character references:

 

the name’s bond… peptide bond references:

Aww look at the 2 cysteines bonding :’)

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All the R groups tryna be fancy

All the R groups tryna be fancy

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